Mixed-Status Latinx Families: Love and Chosen Family as a Means of Resistance to the American Dream

This article is featured in the journal Tapestries: Interwoven voices of local and global identities, volume 4

Pulse Rate Variability for the Assessment of Cardiovascular Changes

Pulse rate variability (PRV) describes the way pulse rate changes through time and is measured from pulsatile signals such as the photoplethysmogram (PPG). It has been proposed as a surrogate for heart rate variability (HRV). Nonetheless, the relationship between these variables is not entirely clear, probably due to both physiological and technical aspects involved in the extraction of PRV. Moreover, the effects of cardiovascular changes on PRV have not been elucidated. In this thesis, four studies were performed to (1) determine the best combination of some technical aspects for the extraction of PRV from PPG signals; (2) evaluate the relationship between PRV and HRV under different cardiovascular conditions; and (3) explore the effects of cardiovascular changes on PRV. First, PRV extraction gave lower errors when (1) signals were acquired for at least 120 s with a 256 Hz sampling rate and filtered with lower low cut-off frequencies and elliptic, equiripple or Parks-McClellan filter; (2) cardiac cycles were determined using the D2max algorithm and the a fiducial points; and (3) the Fast Fourier Transform was applied to obtain frequency spectra. Secondly, the relationship between HRV and PRV was found to be affected by cold exposure and changes in blood pressure, while PRV was found to be different at different body sites. Finally, PRV was affected by haemodynamic changes, such as target flow, stroke rate and blood pressure, both in an in-vitro model and in-vivo data. Additionally, PRV was found to be a potential tool for the estimation of blood pressure, with errors as low as 1:54 ± 0:17 mmHg, 1:07 ± 0:06 mmHg and 1:22 ± 0:09 mmHg for the estimation of systolic, diastolic and mean arterial pressure. Although more studies are needed to fully understand PRV and its clinical potential, PRV should not be regarded as the same as HRV, and it could be consider as a potential valuable biomarker for cardiovascular health

Effects of noise and filtering strategies on the extraction of pulse rate variability from photoplethysmograms

Pulse rate variability (PRV) describes the changes in pulse rate through time, when measured using pulsatile signals such as photoplethysmograms (PPG). PRV has been used as a surrogate of heart rate variability (HRV), but their relationship is not straightforward, both due to physiological differences and to effects of technical aspects on the extraction of PRV information from pulsatile signals such as the PPG. One of the factors that may affect PRV analysis is the presence of noise and the filtering strategy used to pre-process the PPG signal. In this study, the aim was to evaluate the best performing filtering strategy for the extraction of PRV information reliably from noise-contaminated synthetic PPG signals. Time domain, frequency domain and Poincaré plot indices were extracted from PRV trends obtained from the filtered PPG signals and compared against indices measured from a gold-standard simulated PRV function. It was found that PRV information can be reliably extracted from PPG signals filtered using lower low cutoff frequencies and elliptic IIR or equiripple or Parks–McClellan FIR filters, however the filtering parameters depend on the type of noise present in the signal. Moreover, special care should be taken to assess the pNN50 index from contaminated PPG signals, regardless of the type of noise. Future studies should aim to validate these results from real PPG data

Dynamical mechanisms leading to equilibration in two-component gases

Demonstrating how microscopic dynamics cause large systems to approach thermal equilibrium remains an elusive, longstanding, and actively-pursued goal of statistical mechanics. We identify here a dynamical mechanism for thermalization in a general class of two-component dynamical Lorentz gases, and prove that each component, even when maintained in a non-equilibrium state itself, can drive the other to a thermal state with a well-defined effective temperature.Comment: 5 pages, 5 figure

Outlier Management for Pulse Rate Variability Analysis from Photoplethysmographic Signals

Pulse rate variability (PRV) has been proposed as a surrogate for the estimation of Heart Rate Variability (HRV), which is a non-invasive technique used to assess the cardiac autonomic activity. However, both physiological and technical factors may affect the relationship between HRV and PRV, and there are no standards for the analysis of PRV from photoplethysmographic (PPG) signals. The aim of this study was to determine the best outlier management strategies for PRV analysis. 117 PPG signals with randomly generated PRV information were simulated using Gaussian signals. From these, interbeat intervals were detected and different outlier detection and correction techniques were applied. Time and frequency-domain and non-linear PRV indices were extracted and compared with respect to the gold standard values obtained from the simulated PRV information. The results show that, in good quality PPG signals, there is no need to apply any outlier management technique for the extraction of PRV information. Clinical relevance- Establishing guidelines for PRV mea-surement can lead to more reliable and comparable results, as well as to the increase in the use of this variable for the diagnosis and monitoring of cardiovascular and autonomic conditions

Heart Rate Variability and Multi-Site Pulse Rate Variability for the Assessment of Autonomic Responses to Whole-Body Cold Exposure

Heart rate variability (HRV) is a noninvasive marker of cardiac autonomic activity and has been used in different circumstances to assess the autonomic responses of the body. Pulse rate variability (PRV), a similar variable obtained from pulse waves, has been used in recent years as a valid surrogate of HRV. However, the effect that localized changes in autonomic activity have in the relationship between HRV and PRV has not been entirely understood. In this study, a whole-body cold exposure protocol was performed to generate localized changes in autonomic activity, and HRV and PRV from different body sites were obtained. PRV measured from the earlobe and the finger was shown to differ from HRV, and the correlation between these variables was affected by the cold. Also, it was found that PRV from the finger was more affected by cold exposure than PRV from the earlobe. In conclusion, PRV is affected differently to HRV when localized changes in autonomic activity occur. Hence, PRV should not be considered as a valid surrogate of HRV under certain circumstances.Clinical Relevance - This indicates that pulse rate variability is affected differently to heart rate variability when autonomic activity is modified and suggests that pulse rate variability is not always a valid surrogate of heart rate variability

Stabilization of explicit methods for convection diffusion equations by discrete mollification

AbstractThe main goal of this paper is to show that discrete mollification is a simple and effective way to speed up explicit time-stepping schemes for partial differential equations. The second objective is to enhance the mollification method with a variety of alternatives for the treatment of boundary conditions. The numerical experiments indicate that stabilization by mollification is a technique that works well for a variety of explicit schemes applied to linear and nonlinear differential equations